Rexahn Pharmaceuticals, Inc. (RNN) Submits Phase II Protocol to FDA for Clinical Study of Archexin as Treatment for Ovarian Cancer
Yesterday, clinical stage pharmaceutical company Rexahn Pharmaceuticals, Inc. announced it has submitted a phase II protocol to the U.S. Food and Drug Administration for the clinical study of Archexin(R) as a treatment for ovarian cancer. Archexin is a first-in-class Akt protein kinase inhibitor that has the potential utility to inhibit cancer cell survival and proliferation, angiogenesis, and drug resistance. Based on data from the phase I clinical trial, Archexin has an excellent human safety profile, with fatigue as its only side-effect. Archexin has received FDA Orphan drug designation for five difference cancer types, including renal cell carcinoma, glioblastoma and pancreatic,…