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MondayDec 15, 2025 9:45 am

Antisense’s Moment: How Rational Design Is Rewriting Drug Development Economics

Industry data shows small molecules achieve 5–10% approval rates over 15–20 years; antisense oligonucleotides (“ASOs”) are shifting the odds through rational design. Six new antisense drugs gained FDA approval in 2023–2024, bringing total approvals above 20; evidence of accelerating regulatory momentum. Oncotelic Therapeutics’ OT-101 (Trabedersen) is the only TGF-β2-specific antisense in Phase 3 trials, targeting pancreatic cancer and other resistant malignancies. The pharmaceutical industry has long faced sobering odds: about 90% of drug candidates fail before reaching market. For small molecules, approval rates hover at very low odds, often requiring up to two decades of development. In oncology, success rates…

MondayDec 15, 2025 9:35 am

QualityStocksNewsBreaks – GlobalTech Corp. (OTC: GLTK) Names D. Boral Capital as Strategic Advisor for Planned Moda in Pelle Acquisition

GlobalTech (OTC: GLTK), a U.S.-headquartered technology holding company focused on artificial intelligence, big data and emerging technologies, announced that D. Boral Capital LLC has been engaged as strategic advisor in connection with the planned acquisition of 123 Investments Limited d/b/a Moda in Pelle and to provide general financial advisory services related to the transaction. The engagement supports GlobalTech efforts to execute the proposed acquisition, which remains subject to customary agreements, conditions and regulatory compliance, with no assurance that the transaction will be completed. To view the full press release, visit https://ibn.fm/KacrB About GlobalTech Corporation GlobalTech Corporation is a U.S.-based technology…

MondayDec 15, 2025 9:10 am

QualityStocksNewsBreaks – Datavault AI Inc. (NASDAQ: DVLT) Taps Hockey Hall of Famer Jeremy Roenick to Advise International NIL Exchange Initiative

Datavault AI (NASDAQ: DVLT), a provider of patented agentic AI platforms for data observation, valuation and monetization, today announced that Hockey Hall of Famer Jeremy Roenick is advising the Company on the development of its Sports and Entertainment initiative through the forthcoming International NIL Exchange, building on recent partnerships including the World Boxing Council and Dream Bowl. Roenick will support expansion of the platform, which is powered by Datavault AI patented Data Vault, DataScore(R) and DataValue(R) AI agents and enables indexing and tokenization of sports and entertainment assets for trading on the patented Information Data Exchange(R) via the New York…

MondayDec 15, 2025 9:00 am

Xeriant Inc. (XERI) Is ‘One to Watch’

Xeriant offers diversified exposure to next-generation aerospace, advanced materials, and sustainability-focused technologies through its strategic holding-company model. The company’s NEXBOARD product line targets rapidly expanding markets in green construction and fire-resistant materials, supported by ongoing certification efforts and strong early interest from industry partners. Factor X, Xeriant’s innovation division, provides a structured pathway to accelerate commercialization across high-growth sectors through coordinated, interdisciplinary development. Strategic interests in aerospace technologies, including Halo and XTI Aircraft, position the company to participate in long-term shifts toward urban air mobility, VTOL platforms, and advanced aircraft systems. Xeriant’s leadership team brings decades of experience in finance,…

FridayDec 12, 2025 3:32 pm

QualityStocksNewsBreaks – Profit Momentum Builds for Beeline Holdings Inc. (NASDAQ: BLNE) as Next-Gen Platform Accelerates

Beeline Holdings (NASDAQ: BLNE), a fast-growing digital mortgage platform redefining the path to homeownership, recently marked a key accomplishment, with its lending entity generating cash-flow positivity. “The achievement, disclosed in a corporate update on November 11, positions the company to target organization-wide cash-flow positivity in the first quarter of 2026,” reads an article discussing the milestone. “The fintech lender, which focuses on mortgage and home-equity products, has spent the past year streamlining costs while ramping up demand for its AI-powered origination technology. Management noted that cost discipline and what it describes as a scalable lending model have helped move the…

FridayDec 12, 2025 2:43 pm

QualityStocksNewsBreaks – Why SPARC AI Inc. (CSE: SPAI) (OTCQB: SPAIF) Is ‘One to Watch’

Disseminated on behalf of SPARC AI Inc. and may include paid advertising. SPARC AI (CSE: SPAI) (OTCQB: SPAIF), a company focused on developing next-generation software for drones and edge devices, was featured in a recent article that discussed its platform, which transforms unmanned systems into autonomous tools capable of identifying and engaging targets in GPS-denied environments. “The company’s vision is to redefine situational awareness by merging advanced mathematics, AI modeling, and edge computing into a unified intelligence architecture,” the piece reads. “SPARC AI aims to empower defense, rescue, and commercial organizations to operate safely and effectively in signal-contested environments where traditional navigation…

FridayDec 12, 2025 12:45 pm

QualityStocksNewsBreaks – BCII Enterprises Inc. (OTCID: BCII) Details Real-World Applications for Patent-Pending Coupon Token Architecture

BCII Enterprises (OTCID:BCII) today announced real-world applications for its patent-pending Coupon Token architecture, as detailed in two research papers by co-founders Daniel Walsh and Joseph M. Salvani published on the JD Unfiltered platform, outlining deployable, market-based designs to address U.S. housing affordability and the federal debt and deficit. The papers describe a tokenized framework that leverages speculation, trading, and conditional incentives to fund solutions without traditional public spending, while creating scalable revenue opportunities for BCII, including a proposal to issue a single Coupon Token to each of the nation’s approximately 46 million renters that embeds a permanent 2% mortgage rate…

FridayDec 12, 2025 10:30 am

Where Geology Creates Advantage: Inside Search Minerals Inc.’s (TSX.V: SMY) (OTC: SHCMF) Development Across Labrador’s Rare Earth Districts

Disseminated on behalf of Search Minerals Inc. (TSX.V: SMY) (OTC: SHCMF) and may include paid advertising. Search Minerals Inc. controls two district-scale rare earth land packages in Labrador, including the Port Hope Simpson – St. Lewis CREE District and the Red Wine CREE District Each district features many prospects and deposits that the company has explored, sampled, surveyed, and drilled to learn what resides there The districts are home to a range of rare earth elements (“REE”) including Nd (Neodymium), Pr (Praseodymium), Tb (Terbium), Dy (Dysprosium), and other elements and metals that are crucial to the future of the world…

FridayDec 12, 2025 9:45 am

GlobalTech Corp. (GLTK) Acquiring, Building, and Collaborating with Scalable Tech Platforms, Obtaining Interest in a Premium UK Footwear Brand

GlobalTech Corp. is a tech holding company focusing on companies and platforms across AI, big data, and the overall digital infrastructure The company is committed to not only acquiring tech-centric assets with strong growth potential, but also helping them succeed with access to capital, better technology, and more The GLTK portfolio spans a variety of industries, such as digital lending, e-commerce, HR, sports management, and others The company recently announced of a 51% interest in Moda in Pelle (“MIP”), a premium UK footwear brand GlobalTech (OTC: GLTK), a technology holding company focused on acquiring, developing, and scaling AI, big data,…

FridayDec 12, 2025 9:10 am

QualityStocksNewsBreaks – Datavault AI Inc. (NASDAQ: DVLT) Sets Dec. 24 Distribution Date for Dream Bowl 2026 Meme Coin

Datavault AI (NASDAQ: DVLT), a leader in data monetization, credentialing and digital engagement technologies, today announced that its board of directors has set Dec. 24, 2025 as the distribution date for the Dream Bowl 2026 Meme Coin token to all eligible record equityholders of Datavault AI, as well as to record holders of common stock of Scilex Holding Company (NASDAQ: SCLX) receiving the token as a voluntary gesture of appreciation for Scilex’s role as a significant stockholder, licensing partner and co-sponsor of Dream Bowl XIV. The company will begin mailing detailed setup and access instructions on or about Dec. 12,…

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