TG Therapeutics, Inc. (TGTX) Initiates Clinical Trial to Evaluate TG-1101, Lenalidomide Combination
Clinical-stage biopharm company TG Therapeutics today announced that it has initiated a phase I/II trial to evaluate the safety, tolerability, and efficacy of TG-1101, the company’s novel third-generation anti-CD20 monoclonal antibody, in combination with lenalidomide (Revlimid®) for patients with relapsed or refractory B-cell lymphoid malignancies who were previously treated with anti-CD20 antibody therapy. This 30-patient multi-center trial is TG Therapeutics’ second clinical trial of TG-1101 in North America; the company in September began enrollment of its on-going phase I/II trial with single agent TG-1101 in patients with Non-Hodgkin’s Lymphoma (NHL). TG-1101 has displayed high single agent activity in a phase…